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Medical
research
Interpreting MAE research
is difficult and confusing not only because of the medical jargon but
also because the variety of investigators present us with
conflicting definitions, statistics and findings. When reviewing
this material it is important to take note of the submission
date and appreciate that earlier research does not consider newer
medication and better treatment options which have greatly improved outcomes for our children. Also, earlier
definitions of MAE included children who would
no longer be classified as MAE, for example, children who would
nowadays be associated with Severe Myoclonic-Epilepsy of Infancy
(SMEI) or Lennox-Gastaut syndrome (LGS) or Benign Myoclonic
Epilepsy of Infancy (BMEI) which distorted prognosis/outcome
findings. For this reason, earlier research is not truly representative.
Myoclonic Epilepsies -
Advances in Neurology - Volume 95
Publisher : Lippincott
Williams & Wilkins (available via amazon.com and medline.com
Editors: Antonio
Delgado Escueta, Renzo Guerrini, Marco T. Medina, Pierre
Genton,
Michelle Bureau, Charlotte Dravet
Date of publish: 2005
Chapter
11 - Myoclonic-astatic epilepsy of early childhood - definition,
course,
nosography, and genetics (including treatment table)
Neubauer BA, Hahn A, Doose
H, et al
Chapter 12 - Idiopathic
myoclonic-astatic epilepsy of early childhood
- nosology based
on electrophysiologic and long-term follow-up study of patients
by Oguni H, et al
Try your
local epilepsy organisation's library, or you can purchase it from
www.amazon.com. Individual
chapters can be purchased from
www.medline.com.
Delineation of
cryptogenic Lennox-Gastaut syndrome and myoclonic astatic
epilepsy
using multiple correspondence analysis
by Kaminska A, Ickowicz A,
Plouin P, Bru MF, Dellatolas G, Dulac O
Date of publish: 1999
Delineation of LGS & MAE by Kaminska A et
al
Myoclonic-astatic epilepsy
of childhood
by Fritz Dreifuss and Olivier Dulac
Date of submission: August 16, 1993
Date of update: October 2, 1998
Medline SEARCH DATE: September 17, 1998
http://www.ilae-epilepsy.org/Visitors/Centre/ctf/myoclonic_astatic_child.cfm
Treatment and Long-term
Prognosis of Myoclonic-Astatic Epilepsy of Early Childhood
by Hirokazu Oguni et al
Date of publish: Undated, based on patients recruited between
1968 and 1992
Treatment and Long-term Prognosis of MAE
by Oguni et al
Myoclonic-astatic
epilepsy of early childhood
by Herman Doose
Date of publish: 1992
Myoclonic-astatic epilepsy of early
childhood by Herman Doose, 1992 ¨
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